![]() This localized system provides topical therapeutic effects via skin, eyes, nose and vagina to treat. There are some novel topical drugs in the market which can utilise the system as much as possible. The temperature, pH value and dryness of the skin need to be considered. Since skin is the main medium of topical drug delivery system, its conditions determine the rate of skin penetration leading to affecting the pharmacokinetics of the drug. Also, only small particles can pass through the skin, which limits the choice of drugs. However, there are several disadvantages for this system - causing skin irritations and symptoms like rashes and itchiness may occur. All these can increase the patient compliance. There are many advantages for this drug delivery system - avoiding first pass metabolism which can increase its bioavailability, being convenient and easy to apply to a large area, being easy to terminate the medication and avoiding gastro-intestinal irritations. Nowadays, there are numerous dosage forms that can be used topically, including cream, ointment, lotion, patches, dusting powder and much more. The use of topical drug delivery system is much broader now, from smoking cessation to beauty purposes. In ancient times, people used herbs to put on wounds for relieving the inflammatory effect or as pain relievers. This system usually provides a local effect on certain positions of the body. As skin is one of the largest and most superficial organs in the human body, pharmacists utilise it to deliver various drugs. Topical drug delivery is a route of administering drugs via the skin to provide topical therapeutic effects. The word topical derives from Greek τοπικός topikos, "of a place". Topical medications may also be inhalational, such as asthma medications, or applied to the surface of tissues other than the skin, such as eye drops applied to the conjunctiva, or ear drops placed in the ear, or medications applied to the surface of a tooth. Many topical medications are epicutaneous, meaning that they are applied directly to the skin. Most often topical medication means application to body surfaces such as the skin or mucous membranes to treat ailments via a large range of classes including creams, foams, gels, lotions, and ointments. Instilling eye medicationĪ topical medication is a medication that is applied to a particular place on or in the body. JSTOR ( December 2008) ( Learn how and when to remove this template message)Ī medical professional applies nose drops.Unsourced material may be challenged and removed.įind sources: "Topical medication" – news Please help improve this article by adding citations to reliable sources. ![]() This article needs additional citations for verification. ![]()
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